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Glioblastoma Therapeutic Modalities and Proposed Management Protocol

Bekralas Houria 1*, Dr. Habchi Nawel 2

1: Head of Department of Neurosurgery Bejaia Hospital, Bejaia, Algeria

2: Neurosurgery Department, Mustapha Pacha University Hospital, Algiers, Algeria


Glioblastomas are the most common brain tumors in adults. They generally affect adults between the ages of 45 and 65. Treatment of these tumors involves a combination of surgery, radiotherapy and chemotherapy. The prognosis for these processes is usually poor; however, in recent years we have seen advances in the field of clinical research and molecular biology in particular, which give us a glimpse of a glimmer of hope. Prognostic factors have been identified and they make it possible to set up a therapeutic strategy as well as to have an idea of ​​the response to treatment. We report the results of a prospective series of 500 patients operated on by the same surgical team and attempt to propose a management protocol that can serve as a basis for multi-center studies.

Keywords: Glioblastoma, Surgery, Stupp Protocol, Prognostic factors.

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